carcinogenesis
Carcinogenesis involves damage-induced genetic alterations (mutations) that produce cancers. Mutagenesis causes genetic alterations that may, or may not, result in cancer.
Tables Malignant Transformation Oncogenes Proto-oncogenes
Many of the most powerful biological regulators of cell growth and proliferation are encoded by unstable mRNAs, which are targeted for rapid degradation by the cell. The loss of rapid degradation of these growth-promoting mRNAs can result in oncogenic transformation of the cell. Targeted degradation of proto-oncogene mRNAs and short-lived cytokines is controlled both by an AU-rich element (ARE) located in the 3' noncoding region, and by several proteins that bind the ARE sequence. Activation of the ARE for mRNA decay involves cotranslation of the mRNA by ribosomes, and employs the ubiquitin-proteasome pathway.[s]
Carcinogenesis typically results from a series of mutations that affect regulation of proliferation.
m1: inactivation of a tumor suppressor gene results in cell proliferation
m2: mutation inactivates a DNA repair gene
m3: mutation of a proto-oncogene generates an oncogene
m4: mutation inactivates more cancer suppressor genes, resulting in cancerous proliferation
Carcinogenic agents include:
Mutagenic carcinogens
Non-mutagenic carcinogens
Irradiation
Viruses (tumorigenic viruses) Transforming retroviruses and DNA tumor viruses encode oncogenes.
Genetic predisposition (Table of Hereditary Cancers)
Mutagenic carcinogens: ‘genotoxic’ carcinogens are DNA reactive and induce DNA damage. Tobacco smoke is probably the most notorious mutagenic carcinogen, producing, in addition to cardiovascular damage, cancers of the head and neck, lung, and bladder.
Non-mutagenic carcinogens: ‘non-genotoxic’ carcinogens are reported to have have significantly higher computed octanol/water partition coefficients than mutagenic carcinogens, suggesting that their ability to induce tumors may be associated with membraneous receptor sites and/or a longer residence time in the animal [r]. Estrogen can promote the growth of some breast cancers.
Irradiation:
Viruses: transforming retroviruses carry oncogenes mutated from cellular genes that are involved in mitogenic signaling and growth control. DNA tumor viruses encode oncogenes of viral origin that are essential for viral replication and cell transformation; viral oncoproteins complex with cellular proteins to stimulate cell cycle progression and led to the discovery of tumor suppressors. Viral systems support the concept that cancer development occurs by the accumulation of multiple cooperating events.[s]
Genetic predisposition: a variety of inherited genetic abnormalities render affected individuals more prone to malignancy. For example, hereditary non-polyposis colon cancer (HNPCC) is a form of colon cancer frequently associated with defects in the genes encoding MSH2 (about 35% of identified gene-defect cases) and MLH1 (about 60% of identified gene-defect cases). HNPCC is characterized by early age of onset and autosomal dominant inheritance with high penetrance. (Table of Hereditary Cancers)
∞ Cancer ∞ carcinogenesis ∞ oncogenes ∞ proliferation ∞ retroviruses ∞ signaling molecules ∞ tumorigenic viruses ∞ site map ∞
Tables Apoptosis vs Necrosis Apoptosis Cell Adhesion Cell signaling Malignant Transformation Oncogenes Proto-oncogenes Regulatory Proteins Sequences Table of Hereditary Cancers .
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Ferromagnetic Theory of Cancer (Carcinogenesis, Oncogenesis), Laws of Chemistry and Laws of Physics: 1) any cell is a society of dia-, para-, ferri- and ferromagnetic nanoparticles that have local magnetic contacts; 2) cancer 'works' by intracellular superpara-, ferri- and ferromagnetic nanoparticles that can magnetically distort DNA (each human cell contains 2m of DNA); 3) intracellular Fe is ‘the main creator’ of intracellular superpara-, ferri- and ferromagnetic nanoparticles (intracellular masked iron); 4) non-complicated anti-iron Biblical methods can beat any onco-pathology http://www.merriam-webster.com/dictionary/oncogenesis ; http://www.foodconsumer.org/newsite/Non-food/Drug/liver-cancer-treatment_1231111238.html ; http://cancer.blogs.com/international/2009/06/american-cancer-society-partners-with-asco-cancer-foundation-to-train-young-oncologists-from-developing-countries.html ; http://www.medicalnewstoday.com/opinions/69048/ ; http://www.go2web20.net/app/?a=kosmix ; http://cancertreatments.typepad.com/cancer_treatment/2006/09/gastric_bypass.html ; http://www.knowledgerush.com/kr/jsp/db/board.jsp?id=76088 ; http://www.echinacities.com/guangzhou/listing/sun-yat-sen-university-cancer-center.html ; http://www.tutuz.com/metastases-micrometastases-ferromagnetic-theory-cancer/ ; https://getsatisfaction.com/go2web20/topics/allafrica_global_media_ferromagnetic_theory_of_cancer
Aneuploidy Theory of Сancer and Ferromagnetic Theory of Cancer. German pathologist David Hansemann observed (in 1891) asymmetric mitoses in all of the epithelial cancers he examined. This led him to the hypothesis that, “The cell of the malignant tumor is a cell with a certain abnormal chromatin content.”. German biologist Theodor Boveri formulated (in 1914) the aneuploidy theory of cancer. But most researchers have dismissed phenomenon aneuploidy as a byproduct of cancer, not the cause. With the rise in the 1970s of the oncogene theory, the idea that aneuploidy was a cause of cancer was left in the dust. American molecular biologist Peter Duesberg revived the aneuploidy theory in 1997. The prevailing oncogene theory ascribes cancer to a handful of single-gene mutations that sends cells into uncontrolled growth. The aneuploidy theory, on the other hand, hypothesizes that cancer arises from a cell with an abnormal number of chromosomes. The duplicated chromosomes contain extra copies of hundreds or thousands of genes. Certain combinations of aneuploid chromosomes throw the cellular machinery into chaos and thus lead to cancerous growth. As a result of aneuploidy, the total DNA content of a cancer cell can rise to more than twice or fall to nearly half that of a normal diploid cell. In 2007, Scientific American published an article ‘Chromosomal Chaos and Cancer’ by Duesberg. Each cancer is unique. Even if cancers are from the same tissue, and are generated with the same carcinogen, they are never the same. There is always a cytogenetic and a biochemical individuality in every cancer. The Ferromagnetic Theory of Cancer (Theory from The Old Testament): any human cell should be interpreted as a society of dia-, para-, superpara-, ferri- and ferromagnetic nanoparticles. These nanoparticles have certain local magnetic contacts. Any human organism consists of normal cells (cells with non-numerous superpara-, ferri- and ferromagnetic nanoparticles) and tumor cells (cells with numerous superpara-, ferri- and ferromagnetic nanoparticles). Intracellular molecules FeO;Fe2O3;Fe3O4 are the main ‘creators’ of intracellular superpara-, ferri- and ferromagnetic nanoparticles that can chaotically distort DNA and shift chromosomes (by local magnetic fields). “Shift chromosomes” means “confuse, displace, interlace, invert, mix, muddle, permute, remove, transfer or/and transpose chromosomes / chromosomal fragments”. Cancer is a subtle iron disease (hemochromatosis is an obvious iron disease). Oncologists must beat tumors, large metastases and micro-metastases by non-complicated anti-iron methods of The Old Testament. Tigran H. & V. Shapoval http://www.tutuz.com/ South Carolina, USA ; http://www.tutuz.com/spontaneous-remission-cancer-als-aids-ferromagnetic-theory/ ; http://www.medicalnewstoday.com/opinions/38197/ ; http://www.medicalnewstoday.com/opinions/45448/ ; http://www.medicalnewstoday.com/opinions/69048/ ; http://www.medicalnewstoday.com/opinions/77000/ ; http://www.dailycal.org/2011/07/31/study-chaallenges-theory-of-cancer-formation/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Varmus, Duesberg, Shapoval and Ferromagnetic Theory of Cancer. Harold Varmus, M.D., co-recipient of a Nobel Prize for studies of the genetic basis of cancer, was nominated by President Obama as Director of the NCI on May 17, 2010. According to Varmus, the genetic material (DNA) of a cell can become damaged or changed, producing mutations that affect normal cell growth and division. Cells become cancer cells because of DNA damage. The mutation theory of cancer says that a limited number of genes causes cancer. Peter Duesberg is a Professor of Molecular and Cell Biology at the University of California, Berkeley. Duesberg’s arguments derive from his controversial proposal that the mutation theory of cancer - that tumors begin when a handful of mutated genes send a cell into uncontrolled growth - is wrong. Duesberg argues, instead, that carcinogenesis is initiated by a disruption of the chromosomes, which leads to duplicates, deletions, breaks and other chromosomal damage that alter the balance of tens or thousands of genes. The result is a cell with totally new traits - that is, a new phenotype. “I think Duesberg is correct by criticizing mutation theory, which sustains a billion-dollar drug industry focused on blocking these mutations,” said Mark Vincent, a medical oncologist. Vadim Shapoval is a Professor of The Old Testament. According to Shapoval, Varmus and Duesberg ignore Laws of Physics; produce erroneous theories of cancer. Any human cell should be interpreted as a society of dia-, para-, superpara-, ferri- and ferromagnetic nanoparticles. These nanoparticles have certain local magnetic contacts. Superpara-, ferri- and ferromagnetic nanoparticles: 1) strongly attract superpara-, ferri- and ferromagnetic nanoparticles; 2) weakly attract paramagnetic nanoparticles; 3) weakly repel diamagnetic nanoparticles. Any human organism consists of normal cells (cells with non-numerous superpara-, ferri- and ferromagnetic nanoparticles) and tumor cells (cells with numerous superpara-, ferri- and ferromagnetic nanoparticles). Intracellular molecules FeO;Fe2O3;Fe3O4 are the main ‘creators’ of intracellular superpara-, ferri- and ferromagnetic nanoparticles that can chaotically distort DNA and shift chromosomes / chromosomal fragments (by local magnetic fields). The Ferromagnetic Theory of Cancer (Theory from The Old Testament): oncologists must beat cancer (a subtle iron disease) by non-complicated anti-iron methods of The Old Testament. Anti-iron intratumoral injections [sulfur (2%) + olive oil (98%); 36.6C - 39.0C] (by ceramic needles) can suppress any tumors and large metastases. Anti-iron accurate slow blood loss (even 75%) [hemoglobin control], anti-iron goat’s milk diet and anti-iron drinking water containing hydrogen sulfide can neutralize any micro-metastases http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Warburg, Duesberg and Ferromagnetic Theory of Cancer / Carcinogenesis / Oncogenesis. The Warburg Theory of Cancer postulates that tumor cells have defects in mitochondrial oxidative phosphorylation. According to Warburg, cancer should be interpreted as a type of mitochondrial disease. Most modern cancer researchers are convinced that cancer results from a handful of genetic mutations. Peter Duesberg argues that carcinogenesis is initiated by a disruption of the chromosomes. Duesberg’s Chromosomal (Aneuploidy) Theory of Cancer asserts that cancers exhibit a more flexible and unpredictable karyotype, including not only intact chromosomes from the host, but also partial, truncated and mere stumps of chromosomes. The Ferromagnetic Theory of Cancer asserts that cancer should be interpreted as a subtle iron disease. Cancer can be compared with hemochromatosis. Most people store 2-4 grams of iron while those with iron overload may accumulate 20 or more grams. The majority of people with iron overload don't know they have it because they are symptom-free or the disease's symptoms - fatigue, weight loss, joint pain, early menopause, and loss of libido, don't occur until the 40s or older when they may be attributed to other disorders. Over time, the toxic effects of the excess iron can lead to damaging diseases like diabetes, congestive heart failure, and endocrine system problems. Treatment for hemochromatosis involves removing blood from the body, known as phlebotomy. Cancer can attack people even if they store 2-4 grams of iron. Cancer can destroy the human organism by means of 1 gram of iron. Cancer is a serial killer of cancer theories. Hippocrates gave cancer its name. The Old Testament: cancer is the first-born of death. Any cancer and ALS work by intracellular superpara-, ferri- and ferromagnetic nanoparticles. These nanoparticles attract free soluble iron, and thus create deficiency of free soluble iron (create mitochondrial problems) within tumor cells. Moreover, these nanoparticles can chaotically create various errors (mistakes) in DNA; can chaotically disrupt chromosomes (by local magnetic fields). Non-complicated accurate anti-iron methods of The Old Testament can quickly beat any cancer and ALS (intracellular superpara-ferri-ferromagnetic infections) and AIDS (slow virus infection) http://www.dailycal.org/2012/02/22/uc-berkeley-professor-denies-link-between-hiv-and-aids/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Slovak Academy of Sciences, Biogenic Magnetite and Ferromagnetic Theory of Cancer (Carcinogenesis, Oncogenesis). The Slovak Academy of Sciences studies the biogenic magnetite (Fe3O4) in humans. The biogenic magnetite was found in several biological species, including mammals. It is believed that the magnetite biomineralization is a genetically-controlled biochemical process, through which organisms make perfect ferrimagnetic crystals. However, this process is still not well understood. Magnetic measurements on samples of human tissue confirmed the presence of trace quantities of stable single domain magnetite particles in virtually all human tissues. Although, several ideas about the biological function of magnetite in humans have been proposed, the real purpose is still not known. Several studies suggested that levels of biogenic magnetite in human brain tissue may be elevated in subjects with Alzheimer disease or associated with aging. Biogenic magnetite in human tissue represents biologically produced ferrimagnetic nanoparticles. We do not know its function, but if we accept, that in animals it plays a crucial role in geomagnetic field navigation, we also have to accept interaction with neurosensory system through biochemical bonds. Without precise knowledge of biogenic magnetite physiological function and interaction with surrounding environment, it is more or less hypothetical to describe precise mechanisms of hazardous interaction. However, our preliminary simulations indicate potential health hazard impact of such interaction. To understand the precise mechanism of interaction in humans, we need to clarify two basic things. First, what is the physiological function of such nanoparticles and what is their spatial arrangement in tissue? Second, what is the biological response of organism to applied fields? The situation in MR devices is much more extreme, so it can be more “detectable” and can bring new views to the problem of (electro-) magnetic field interaction with living systems. Ferromagnetic Theory-2006 of Cancer and Ferromagnetic Theory-2010 of ALS: Cancer and ALS work by biologically produced ferrimagnetic nanoparticles (Fe3O4) within cells. Human tissues are not ferro(i)magnetic, but ferro(i)magnetic nanoparticles can be present as contaminants within cells. Intracellular ferro-, ferri- and superparamagnetic nanoparticles can 'attack' DNA and chromosomes by invisible local magnetic fields (by elastic forces). Hemochromatosis (iron overload disorder) provokes the formation of Fe3O4 within cells. The most common complications of hemochromatosis are liver cancer and other types of cancer. Fe3O4 has ferro-, ferri- and superparamagnetic helpers. Cobalt nanoparticles 'create' cobalt-induced carcinogenesis. Nickel nanoparticles 'create' nickel-induced carcinogenesis. An oncovirus (tumor virus, cancer virus) is a virus that can cause cancer. Any oncovirus is a superparamagnetic nanoparticle. Asbestos particles contain ferri- and ferromagnetic nanoparticles. Chemical carcinogenic nanoparticles (asbestos, 3,4-benzpyrene, aflatoxins, etc.) are ready superpara-, ferri- and ferromagnetic nanoparticles. These nanoparticles can pass through cell membranes and 'create' chemical-induced carcinogenesis. Non-complicated anti-iron methods of The Old Testament will beat Cancer and ALS (Fe3O4-diseases) and AIDS (slow virus infection). The Slovak Academy of Sciences can develop the Ferromagnetic Theory-2006 of Cancer / Carcinogenesis and the Ferromagnetic Theory-2010 of ALS http://www.measurement.sk/2011/Strbak.pdf ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Difference between Tumor Cells and Normal Cells. Contact inhibition is the natural process of arresting cell growth when two or more cells come into contact with each other. Contact inhibition controls cell growth by allowing cells to replicate as old cells die but keeps unnecessary tissues from forming in their place. Normal cells have their own identity and obey the rule of contact inhibition. Normal cells adhere to each other and expire at the end of their life cycles. Tumor cells typically lose these properties and thus grow in an uncontrolled manner even when in contact with neighboring cells. Tumor cells do not follow the rules of contact inhibition, adherence and self-destruction (apoptosis, programmed cell death). Usually, tumor cells contain faulty DNA and chromosomes (some chromosomes may be duplicated or deleted). Tumor cells spread through the body via the lymphatic and circulatory systems. Clearly, tumor cells evade the immune system (tumor cells can trick the immune system). Unlike normal cells that are specialized, tumor cells are non-specialized and do not contribute to the functioning of a body part. Normal cells have specialized behaviors and serve a purpose. Tumor cells have lost their specialized function. The first tumor cells (in the human body) are not very malignant cells; subsequent (mature) tumor cells are extremely malignant cells. Ordinarily, old normal cells undergo apoptosis, a series of enzymatic reaction that lead to the death of the cell. Normal cells will self-destruct if genetic / chromosomal abnormalities are found. Tumor cells fail to undergo apoptosis. Normal cells divide about 50 times and then stop dividing and die. Tumor cells can enter the cell cycle repeatedly, and in this way, they are potentially immortal. According to the Ferromagnetic Theory of Cancer / Carcinogenesis / Oncogenesis / Tumorigenesis (Iron Conception), any tumor cells are cells with numerous intracellular superpara-, ferri- and ferromagnetic nanoparticles. Any normal cells are cells with non-numerous intracellular superpara-, ferri- and ferromagnetic nanoparticles. Any cancer and ALS work by these nanoparticles. Tumor cells (cells with these nanoparticles; excessively negatively charged cells) do not follow the rules of contact inhibition and adherence. Enzyme activity can be affected by these nanoparticles (immortality of tumor cells). The immune system does not identify these nanoparticles within cellular organelles (the immune system can’t distinguish between dia-, para-, superpara-, ferri- and ferromagnetic micro- and nano-objects). These nanoparticles can chaotically-anarchically distort DNA and shift chromosomes by local magnetic fields (mistakes in DNA; chromosomal faults; deformed mitoses; non-specialization and ugliness of tumor cells). Oncologists-clinicians must beat cancer (a subtle iron disease) by non-complicated anti-iron methods of The Old Testament http://www.medicalnewstoday.com/opinions/35502/ ; http://www.medicalnewstoday.com/opinions/69048/ ; http://www.knowledgerush.com/kr/jsp/db/board.jsp?id=81898 ; http://www.tutuz.com/spontaneous-remission-cancer-als-aids-ferromagnetic-theory/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Vadim Shapoval
Iron Chelators for Cancer Therapy and Ferromagnetic Theory of Cancer. Observations that rapid neoplastic cell proliferation requires iron have led to the understanding that some iron chelators may be useful against cancer. Researchers endeavor to develop more effective iron chelators for cancer therapy. Chelation is a very effective way to treat heavy-metal poisoning. Since the 1970s, iron chelation therapy (the removal of excess iron from the body with special drugs) has been used as an alternative to regular phlebotomy to treat excess iron stores in people with hemochromatosis. The goal of iron chelation therapy is to prevent iron-mediated injury to cells. Researchers can't beat cancer by iron chelators because: 1) researchers invent ultra-complicated iron chelators; 2) researchers mix anti-cancer iron chelation therapy with chemotherapy and radiation therapy. According to the Ferromagnetic Theory-2006 of Cancer (Iron Conception), any tumor cells are cells with numerous intracellular superpara-, ferri- and ferromagnetic nanoparticles (any normal cells are cells with non-numerous intracellular superpara-, ferri- and ferromagnetic nanoparticles). Researchers must beat cancer (a subtle iron disease) by non-complicated iron chelators of The Old Testament: 1) intratumoral injections [sulfur (2%) + olive oil (98%); 36.6C – 39.0C] (by ceramic needles) [suppression of tumors and large metastases]; 2) accurate slow blood loss (even 75%) [hemoglobin control] (neutralization of micro-metastases); 3) goat’s milk diet and anti-iron drinking water containing hydrogen sulfide (neutralization of micro-metastases). http://www.medicalnewstoday.com/opinions/35502/ ; http://www.medicalnewstoday.com/opinions/38197/ ; http://www.medicalnewstoday.com/opinions/45448/ ; http://www.medicalnewstoday.com/opinions/69048/ ; http://www.medicalnewstoday.com/opinions/77000/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Vadim Shapoval
Otto Warburg and Somatic Evolution. According to Dr. Otto Warburg, there are prime and secondary causes of diseases. For example, the prime cause of the plague is the plague bacillus, but secondary causes of the plague are filth, rats, and the fleas that transfer the plague bacillus from rats to man. Cancer, above all other diseases, has countless secondary causes. Almost anything can cause cancer. But, even for cancer, there is only one prime cause. The prime cause of cancer is the replacement of the respiration of oxygen (oxidation of sugar) in normal body cells by fermentation of sugar. All normal body cells are thus obligate aerobes, whereas all cancer cells are partial anaerobes. Cancer should be interpreted as a type of mitochondrial disease. The multistep process of carcinogenesis is often described as Somatic Evolution. The transition from normal tissue to invasive cancer is a multistep, multipath process in which increasingly malignant cellular populations emerge over time generally coincident with accumulating genomic mutations. According to The Old Testament and The Ferromagnetic Theory of Cancer / Carcinogenesis (Iron Conception), any human cell should be interpreted: 1) as a society of atoms and molecules; 2) as a society of organelles; 3) as a society of dia-, para-, superpara-, ferri- and ferromagnetic nanoparticles that have certain local magnetic contacts. An atom is the smallest unit of matter. Atoms are the chemical units of cell structure. Atoms form molecules when two or more are bonded together. The human body contains many different organs. Cells also have a set of little organs, called organelles. Cells obey the same laws of chemistry and physics that determine the behavior of nonliving systems. Cancer works by intracellular superpara-, ferri- and ferromagnetic nanoparticles that can chaotically distort DNA and shift chromosomes by local magnetic fields; can affect intracellular molecules and organelles (mitochondria, lysosomes, etc.). Cancer is intracellular superpara-ferri-ferromagnetic 'infection'. Oncologists must beat cancer by non-complicated anti-iron methods of The Old Testament. http://www.medicalnewstoday.com/opinions/38197/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Iron Blood Serum Levels, Hemochromatosis and Carcinogenesis. All human cells, including blood cells, contain iron. A healthy person should have a normal iron blood serum level in the range of 60 to 170 micrograms per decilitre of blood. There are four tests available to determine a person's level of iron in the bloodstream: the Iron-Binding Capacity Test (TIBC), the Ferritin Test, the Transferring Test and the Serum Iron Test. These tests are used to determine if someone is suffering from anemia or too much iron as well as what treatment is needed for a particular condition. Disorders that benefit from iron level testing are gastrointestinal bleeding, iron poisoning, thalassemia, hemosiderosis and hemochromatosis. Hemochromatosis is the abnormal accumulation of iron in parenchymal organs. Cancer is the abnormal accumulation of nano-crystalline iron (superparamagnetic, ferrimagnetic and ferromagnetic nano-particles) in cancer cells. Cancer can attack persons with low, normal or high iron blood serum levels. That's why cancer researchers invent 'non-iron cancer theories'. Iron Conception (Ferromagnetic Cancer Theory) / (Ferromagnetic Theory of Carcinogenesis): oncologists can beat any cancer (a subtle iron disease) by non-complicated anti-iron methods of The Old Testament. http://www.medicalnewstoday.com/opinions/45448/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Warburg, DKFZ and Ferromagnetic Theory of Cancer. Otto Warburg was a German physiologist, medical doctor and Nobel laureate. The Warburg Theory of Cancer or 'Warburg hypothesis' postulates that the driver of carcinogenesis is an insufficient cellular respiration caused by insult to mitochondria. DKFZ (Deutsches Krebsforschungszentrum) is a national cancer research center based in Heidelberg, Germany. According to DKFZ, cancer is a disease that poses enormous challenges to research, because every cancer is different and its course can vary immensely even from one patient to the next. Every year, in Germany more than 450,000 people develop cancer; more than 216,000 people die of cancer. According to the Ferromagnetic Theory of Cancer (Theory from The Old Testament), cancer is a subtle iron disease. Cancer is the abnormal (excessive) accumulation of superparamagnetic, ferrimagnetic and ferromagnetic nano-particles in tumor cells. These nano-particles: 1) create deficiency of intracellular heme iron and non-heme iron in tumor cells; 2) suppress mitochondrial and lysosomal enzymes; 3) weaken and destroy mitochondria and lysosomes ('suicide-bags') in tumor cells; 4) chaotically distort DNA and shift chromosomes by local magnetic fields. That's why Otto Warburg argued, cancer should be interpreted as a type of mitochondrial disease. That's why scientists describe tumor cells as being 'immortal'; cancer as a genetic disease or as chromosomal chaos. DKFZ can beat cancer by non-complicated accurate anti-iron methods of The Old Testament. http://www.medicalnewstoday.com/opinions/38197/ ; http://www.dkfz.de/en/dkfz/index.html ; http://en.wikipedia.org/wiki/German_Cancer_Aid ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Carcinogens and Ferromagnetic Cancer Theory. Carcinogens are agents that can cause cancer. Exposure to one or more carcinogens, including certain chemicals, radiation, and certain viruses, can initiate cancer. Repeated local injury or irritation to a part of the body can be carcinogenic. In some cases, substances that are helpful to man are also carcinogenic. According to the Ferromagnetic Cancer Theory (Theory from The Old Testament; Iron Conception), any human can get cancer because any human cell contains intracellular iron carcinogen (FeO;Fe2O3;Fe3O4). Martha Tracy (American cancer researcher, Cornell University Medical College, New York City, 1905) called this carcinogen "Masked" Iron. Other researchers call this carcinogen Biogenic Ferrimagnetic Magnetite. The concentration of magnetite nanocrystals in human brain tissues is 3 - 10 ng/g tissue. Any human cell should be interpreted: 1) as a society of atoms and molecules; 2) as a society of organelles; 3) as a society of diamagnetic, paramagnetic, superparamagnetic, ferrimagnetic and ferromagnetic nanoparticles that have certain local magnetic contacts. Intracellular molecules FeO;Fe2O3;Fe3O4 are the main 'creators' of intracellular superparamagnetic, ferrimagnetic and ferromagnetic nanoparticles. Any cancer is a subtle iron disease. Intracellular superpara-ferri-ferromagnetic nanoparticles can chaotically distort DNA and shift chromosomes. Cancer researchers invent Genetic Cancer Theory and Chromosomal (Aneuploidy) Cancer Theory. Carcinogens are agents that can initiate and accelerate FeO;Fe2O3;Fe3O4-crystallization within cell. Non-complicated ancient anti-iron medical methods of The Old Testament can successfully beat any cancer. http://www.medicalnewstoday.com/opinions/72146/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Cancer, ALS, AIDS, Religious Beliefs of Patients and Medicine-2013. Scientists can't beat cancer, ALS and AIDS. Cancer has a reputation as a deadly disease. ALS is a devastating and fatal neurological disorder. Since the beginning of the epidemic, nearly 30 million people have died from AIDS-related causes. Scientists ignore iron-cancer, iron-ALS and iron-AIDS scientific data. In the past, scientists ignored scientific 'antibiotic data'. In 1871-1872 V. Manassein and A. Polotebnov used antibiotic properties of fungi (green or blue molds on decaying food). In 1928 Alexander Fleming discovered penicillin. It became widely used during World War II. Howard Florey and Ernst Chain took up Fleming's research and found a way to purify penicillin. Chemotherapy of virus diseases is an extremely interesting but, at the same time, a very difficult problem. At present, there are no effective therapeutic agents for the treatment of many virus infections. Chemotherapy of malignant tumors, like that of virus diseases, presents considerable difficulties because the difference between the metabolism of tumor cells and that of normal cells is negligible. All types of tissues and cells of the macro-organism may undergo malignant degeneration, which makes difficult the search for drugs that would have a selective effect on the tumor tissues and would not affect the healthy ones. Scientists ignore information: a human organism can survive 'accurate anti-iron aggression'; cancer, ALS and HIV/AIDS can't survive 'accurate anti-iron aggression'. All forms of cancer are caused by intracellular superpara-ferri-ferromagnetic 'infection'. All forms of ALS are caused by intraneuronal superpara-ferri-ferromagnetic 'infection'. Any somatic cell / any neuron should be interpreted as a society of dia-, para-, superpara-, ferri- and ferromagnetic nanoparticles. Enzyme systems of any virus contain heme iron and non-heme iron. Deficiency of iron destabilizes enzyme systems of any virus. Slow blood loss (even 75%) [hemoglobin control], goat’s milk diet and drinking water containing hydrogen sulfide can gradually neutralize intracellular / intraneuronal superpara-ferri-ferromagnetic nanoparticles and enzyme systems of HIV. Any micrometastases and isolated tumor cells will weaken. Moreover, according to the Ferromagnetic Cancer Theory (Theory from The Old Testament; Iron Conception), ceramic needles can enter solution [sulfur (2%) + olive oil (98%); 36.6C - 39.0C] to tumors and large metastases, 'individuals with mutilated DNA', who live within religious and non-religious cancer patients. Carcinogenesis 'typically results from a series of mutations that affect regulation of proliferation'. Medicine-2013 will beat cancer, ALS and HIV/AIDS by non-complicated anti-iron methods of The Old Testament. http://www.medicalnewstoday.com/opinions/103745/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Spontaneous Remission of Cancer and Ferromagnetic Cancer Theory. Spontaneous remission (SR) of cancer is defined as the disappearance, complete or incomplete, of cancer without medical treatment, or with treatment that is considered inadequate. Some researchers have hypothesized that SR may be caused by bacterial infection, blood transfusion, minor or major surgery. The case of a metastatic gastric cancer patient who experienced SR after a surgery-induced bacterial infection (Rosenberg, Fox, Churchill, 1972) has strongly contributed to the modern field of cancer immunotherapy, which injects small doses of bacteria into a tumor in order to stimulate the immune system to recognize and remove the tumor. Other SR-researchers: 1) SR occurs when certain elements that are necessary for a tumor’s survival are sharply reduced in the body; 2) hormonal changes may elicit SR. Leukemia can spontaneously receive regress before or after childbirth. SR-researchers have hypothesized that a severe reduction in thyroid hormone may lead to the SR of lung cancer, and that reduced thyroid levels may be applicable to all types of cancer in terms of eliciting SR. Iron deficiency anemia is associated with lower plasma thyroid hormone concentrations in humans. Everson and Cole in 1976 reviewed 176 well documented cases of SR of cancer and suggested that blood transfusion was the trigger for the remission. On the other hand, other clinicians have claimed that removing plasma from patients with metastatic cancer may induce remissions. Patients who have not received a blood transfusion before, during, or after their operation for colorectal cancer survive longer without tumor recurrence. According to the Ferromagnetic Cancer Theory (Iron Conception), any cancer is a subtle iron disease; intracellular superpara-ferri-ferromagnetic 'infection'; the first-born of death (The Old Testament; Job 18:13-15). Bacterial and viral infections, slow blood loss, minor or major surgery, pregnancy and childbirth, lower plasma thyroid hormone concentrations ARE 'spontaneous iron chelation events'. Oncologists must beat any tumors, metastases and micro-metastases by iron chelation therapy of The Old Testament. Ceramic needles can suppress any tumors and large metastases. Ceramic needles can create harmless infiltrations (harmless necroses, deposits of cells that die; benign capsules). Ceramic needles can enter solution [sulfur (2%) + olive oil (98%); 36.6C - 39.0C] to tumors and large metastases. Slow blood loss (even 75%) [hemoglobin control], goat’s milk diet [Thou shalt not seethe a kid in his mother's milk; Deuteronomy 14:21] and drinking water containing hydrogen sulfide can neutralize any micrometastases or isolated tumor cells. Medical News Today & Ferromagnetic Cancer Theory http://www.medicalnewstoday.com/opinions/44497/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Shapoval
Sarcomas and Ferromagnetic Cancer Theory. There are numerous types of sarcomas that can affect different parts of the body; however, they have similar characteristics and symptoms, and medical treatments are similar. Sarcoma is an uncommon and often malignant tumor. Benign tumors rarely recur, but sarcomas can reappear after treatment. The percentage of people diagnosed with sarcoma who survived 5 years later is only 50%. This includes all patients suffering from all types of sarcomas. There is an acute need to develop entirely new treatment strategies for the treatment of sarcomas. For most types of sarcomas, the major cause of death is metastatic disease. There are certain types of sarcomas in which metastases rarely occur but uncontrolled local growth represents the major therapeutic problem. Surgery is the most common treatment for sarcoma. If the tumor cannot be removed surgically, it may be permanently controlled with radiation therapy. Chemotherapy and/or radiation therapy: 1) may be given before or after surgery to reduce the risk of recurrence; 2) may also be used to reduce the size of the sarcoma or relieve pain and other symptoms. If the sarcoma is found to have a specific chromosomal abnormality, the targeted therapy may be used in some patients. Oncologists use interferon for patients with osteosarcomas and imatinib for patients with gastrointestinal sarcomas. Ferromagnetic Cancer Theory (Theory from The Old Testament; Iron Conception) offers to treat all types of sarcomas by intratumoral injections of solution [sulfur (2%) + olive oil (98%); 36.6C - 39.0C]. These intratumoral injections by ceramic needles: 1) can create harmless infiltrations (harmless necroses; deposits of cells that die; benign capsules); 2) can suppress secondary bacterial infection (oncopatients have a significant risk for infection due to their treatment). The intratumoral anti-iron treatment can chemically eliminate any sarcomatous tumors and large metastases. Anti-iron slow blood loss (even 75%) [hemoglobin control], anti-iron goat’s milk diet and anti-iron drinking water containing hydrogen sulfide can neutralize any micrometastases and isolated tumor cells. http://www.medicalnewstoday.com/opinions/114087/ ; http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Vadim Shapoval
Father of Oncology, Ferromagnetic Cancer Theory, US Thermonuclear Sun-2018 and Chinese Lunar Robots. The origin of the word CANCER is credited to the Greek physician Hippocrates (460-370 BC), who is considered the Father of Medicine. Rudolf Virchow, also known as the Father of Pathology, stated that no man, even under torture, can say exactly what a tumor is. Medical News Today is a Leading Resource for the latest news on cancer. According to MNT, cancer is ultimately the result of cells that uncontrollably grow and do not die. Vadim Shapoval (born August 11, 1969), also known as the Father of Oncology, as the Father of the Thermonuclear Sun-2018, states that cells obey the same laws of chemistry and physics that determine the behavior of nonliving systems. Cancer is a disease of cells. Any human cell is composed of water; diamagnetic, paramagnetic, superparamagnetic, ferrimagnetic and ferromagnetic nanoparticles. Tumor cells are riddled with genetic errors. The body has no natural way to rid itself of the excess iron. Any cancer is caused by iron-related genes (genes involved in iron metabolism) and iron-related events (when excess iron accumulates in the cells, tissues, and organs due to various causes). Any cancer is a subtle iron disease; intracellular superpara-ferri-ferromagnetic infection; death's firstborn who devours limbs (Job 18:13). According to the Ferromagnetic Cancer Theory (Theory from The Old Testament; Iron Conception), ancient accurate anti-iron methods can beat any cancer. After Stalin died in 1953, the TOKAMAK was developed in the mid-1960s by Soviet plasma physicists. TOKAMAK is Soviet Scientific Fraud. STELLARATOR is a device used to confine hot plasma with magnetic fields. Tokamaks and Stellarators must die. Chinese physicists should know American thermonuclear technologies. Petroleum and wheeled vehicles will die soon. US will create the Greatest Source of Electricity. US Nuclear Artillery will initiate the work of US Thermonuclear Sun-2018 in granite quarry. A star is a massive sphere of plasma held together by its own gravity. A star's life begins with the gravitational collapse of a gaseous nebula of material composed primarily of hydrogen, along with helium and trace amounts of heavier elements. Life of US Thermonuclear Sun will begin with the non-gravitational collapse of thermonuclear fuel (tritium, deuterium, lithium deuteride and LUNAR helium-3). Special artillery (numerous guns) will create (towards each other) non-gravitational collapse and will deliver thermonuclear fuel to the Thermonuclear Sun. It has been estimated that there are around 1100000 metric tons of helium-3 on the surface of the Moon down to a depth of a few meters. Russia, India, Japan and Germany are taking an interest in lunar exploration linked to helium-3 as a potential thermonuclear fuel. Chinese lunar robots must go to the Moon to mine helium-3 for US Thermonuclear Sun-2018. http://oncologic.blogspot.com/2007/12/carcinogenesis.html ; Together We (Medical News Today, TIME, Merriam-Webster and Vadim Shapoval) Will Beat CANCER